Research Article

Outcome of Trabeculectomy in Advanced Glaucoma in a tertiary hospital in Rivers State, Nigeria

Awoyesuku EA* and Fiebai B

Published: 19 December, 2018 | Volume 2 - Issue 2 | Pages: 027-031

Aim: To evaluate the outcome of Trabeculectomy in advanced glaucoma in a hospital in Rivers State, Nigeria.

Methods: This was a non-randomized interventional study in which each patient served as its own control. Patients with advanced glaucoma and demonstrable field defects and Mean defect ≥-12 were included. The intervention employed was Trabeculectomy and IOP and visual acuity pre operative, as well as post op were collected and compared at pre- op, post -op day 1, one week, one month, 6 months. Data was analyzed using SPSS version 20.

Results: Thirteen (13) eyes from ten (10) patients with advanced glaucoma were involved in the study. Mean age of study population was 53±19.62 years. Mean of mean defect was -19.05±5.23dB while mean of vertical cup disc ratio (VCDR) was 0.88±0.04.

Mean of Pre- op Visual acuity (log MAR) was 0.46 and dropped to 0.72 first day post-op but improved over 6 months to 0.42. The mean of IOP pre-op was 24.15mmHg and dropped to 11.23mmHg (58.24%) over 6 months (p=0.001).

Conclusion: Trabeculectomy still remains the gold standard surgical treatment for glaucoma. In our study it resulted in a 58.24% drop in IOP over 6 months with mean visual acuity maintained at pre-op levels after 6 months follow up. It therefore is effective and safe surgical intervention in advanced glaucoma.

Read Full Article HTML DOI: 10.29328/journal.ijceo.1001018 Cite this Article Read Full Article PDF


Advanced glaucoma; Intra ocular pressure; Trabeculectomy; Visual acuity


  1. Quigley HA. The number of people with glaucoma worldwide. Br J Ophthalmol. 1996; 80: 389-393. Ref.: https://goo.gl/qfe66M
  2. Abdul MM, Sivasubramaniam S, Murthy G, Gilbert C. Causes of blindness and visual impairment in Nigeria: the Nigerian blindness and visual impairment survey. Invest Ophthalmol & Vis Sci. 2009; 50: 4114-4120. Ref.: https://goo.gl/ST9V5n
  3. Awoyesuku EA, Ejimadu CS. Visual disability from Primary Open Angle Glaucoma (POAG) in University of Port Harcourt Teaching Hospital. Niger J Med. 2012; 21: 78-80. Ref.: https://goo.gl/R69Nfh
  4. Omoti AE, Osahon AI, Waziri-Erameh MJ. Pattern of presentation of primary open-angle glaucoma in Benin City, Nigeria. Tropical Doctor. 2006; 36: 97-100. Ref.: https://goo.gl/iDTwgS
  5. Dawodu OA, Osahon AI, Emifoniye E. Prevalence and causes of blindness in Otibhor Okhae Teaching Hospital, Irrua, Edo State, Nigeria. Ophthalmic Epidemiol. 2003; 10: 323-330. Ref.: https://goo.gl/QVY9ff
  6. Stead RE, King AJ. Outcome of Trabeculectomy with Mitomycin C in patients with advanced glaucoma. Br J Ophthalmol. 2011; 95: 960-965. Ref.: https://goo.gl/9CCjeC
  7. Anand N, Mielke C, Dawda VK. Trabeculectomy outcomes in advanced glaucoma in Nigeria. Eye (Lond) 2001; 15: 274-278. Ref.: https://goo.gl/nfYYQP
  8. Baser EF, Seymenoglu G, Mayali H. Trabeculectomies for advanced glaucoma. Int Ophthalmol. 2011; 31: 439-446. Ref.: https://goo.gl/7jYNT2
  9. King AJ, Fernie G, Azuara-Blanco A, Burr JM, Garway-Heath T, et al. Treatment of Advanced Glaucoma Study: a multicentre randomized controlled trail comparing primary medical treatment with primary Trabeculectomy for people with newly diagnosed advanced glaucoma-study protocol. Br J Ophthalmol. 2018; 102: 922-927. Ref.: https://goo.gl/jRxEjD
  10. Peters D, Bengtsson B, Heijl A. Factors associated with lifetime risk of open-angle glaucoma blindness. Acta Ophthalmol. 2014; 92: 421-425. Ref.: https://goo.gl/mw2cGv
  11. Anthony King, Augusto Azuara-Blanco, Anja Tuulonen. Clinical Review Glaucoma. BMJ 2013; 346: f3518. Ref.: https://goo.gl/uNDV9g
  12. Francis BA, Hong B, Winarko J, Kawji S, Dustin L, et al. Vision loss and Recovery after Trabeculectomy, risk and associated risk factors. Arch Ophthalmol. 2011; 129: 1011-1017 Ref.: https://goo.gl/jHhjNh
  13. Soatiana JE, Kpoghoumou MA, Kalembo FW, Zhen HH. Outcomes of Trabeculectomy in Africa. Open Journal of Ophthalmology; 2013; 3: 76-86. Ref.: https://goo.gl/gwpcC3
  14. Ndife TI, Abdullahi SM, Raji L, Umar MM, Olaniyi S, et al. Long-term outcome of Trabeculectomy with and without small incision cataract surgery at a tertiary eye hospital in Northern Nigeria. Niger J Ophthalmol. 2017; 25: 110-113 Ref.: https://goo.gl/8T5inQ
  15. A Lawan. Pattern of presentation and outcome of surgical management of primary open angle glaucoma in Kano, Northern Nigeria. Ann Afr Med. 2007; 6: 180-185. Ref.: https://goo.gl/CSBBME
  16. Adegbehingbe BO, Majemgbasan T. A review of Trabeculectomies at a Nigerian Teaching Hospital. Ghana Med J. 2007; 41: 176-180. Ref.: https://goo.gl/EV5opZ
  17. Thommy CP, Bhar IS. Trabeculectomy in Nigerian patients with open angle glaucoma. Br J Ophthalmol. 1979; 63: 636-642. Ref.: https://goo.gl/w2kHBi
  18. Kizor- Akaraiwe NN, Ogbonnaya CE. Practice of Trabeculectomy by Ophthalmologists in Nigeria. Niger J Clin Pract. 2017; 20: 507-511. Ref.: https://goo.gl/a6y3BY


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