Prospective Clinical Study to Find out Epidemiology of Xerophthalmia in Children in a Tertiary Care Centre in India
Main Article Content
Abstract
Objective: To study the epidemiology of xerophthalmia in children 2-6 years of age in North India.
Methods: A prospective clinical study was done at two tertiary care centers of North India between 2010 to 2016, Cases were selected from routine OPD and children less than 6 years of age were examined by an ophthalmologist. Diagnosis and classification of Xerophthalmia was done according to WHO classification. All the data recording demographic profile, socioeconomic status, other health problems etc were recorded in a fixed proforma. Data was analyzed by SPSS version 16.
Findings: Two thousand nine hundred forty six cases were included in the study after satisfying inclusion and exclusion criteria. The prevalence of night blindness was estimated to be 2.93% (95% Confidence Interval [CI]: 2.53-3.33) among children between 2 and 6 years of age. Xerophthalmia prevalence was 4.43% (95% CI: 4.19-4.67). Prevalence was more in girls than boys and higher in low socioeconomic status.
Conclusion: Vitamin A deficiency is recognized to be a severe public health problem leading to corneal opacity and childhood blindness in most of the areas of North India
Article Details
Copyright (c) 2017 Mishra D. et al.

This work is licensed under a Creative Commons Attribution 4.0 International License.
Sommer A, West KP Jr. Vitamin A Deficiency: Health, Survival, and Vision. New York, Oxford University Press. 1996.
Underwood BA, Arthur P. The contribution of vitamin A to public health. FASEB J. 1996; 10: 1040-1048. Ref.: https://goo.gl/5tKAu6
Sherwin JC, Reacher MH, Dean WH, Ngondi J. Epidemiology of vitamin A deficiency and xerophthalmia in at-risk populations. Trans R Soc Trop Med Hyg. 2012; 106: 205-214. Ref.: https://goo.gl/khARNF
Bahreynian M, Qorbani M, Naderimagham S, Nejatinamini S, Ataie-Jafari A. Burden of disease attributable to vitamin A deficiency in Iranian population aged less than five years: findings from the global burden of disease study 2010. J Diabetes Metab Disord. 2017; 16: 32. Ref.: https://goo.gl/ke1qfY
Garg S, Nayar S, Garg A, Sane S. Vitamin A deficiency in preschool children. Indian Pediatrics. 1984; 21: 491-494. Ref.: https://goo.gl/2Dws5P
Sharma SK, Mathur GP, Mathur S, Singh Y. An epidemiological study of hypovitaminosis a in preschool children of urban slums in Gorakhpur. Indian J Prev Soc Med. 1985; 16: 131-136.
Katiyar GP, Jaiswal P, Reddy DCS, Agrawal, KN. Biosocial determinants of xerophthalmia in under-five children. Indian J Prev Soc Med. 1986; 17: 69-78.
Kartha GP, Purohit CK. Prevalence of xerophthalmia-an evaluation in the context of ongoing National vitamin A supplementation program in five villages of Dholka Taluka of Ahmedabad District. Indian J Com Med. 1991; 16: 115-8.
Sampathkumar V, Abel R. Xerophthalmia in rural South Indian children. Indian Pediatrics. 1993; 30: 246-248. Ref.: https://goo.gl/Y8LK1g
Fakhir S, Srivastava I, Ahmad P, Husan SS. Prevalence of xerophthalmia in preschool children in an urban slum. Indian Pediatr. 1993; 30: 668-670. Ref.: https://goo.gl/8uRGzp
Chamani N, Sharma P, Meena N, Sharma U. Pattern of vitamin deficiencies among the malnourished preschool children in ICDS blocks of Jaipur city. Indian J Matern Child Health. 1994; 5: 109-111. Ref.: https://goo.gl/2x2eaD
Pal R, Sagar V. Antecedent risk factors of xerophthalmia among Indian rural preschool children. Eye Contact Lens. 2008; 34: 106-108. Ref.: https://goo.gl/JCjsjb
Control of vitamin A deficiency and xerophthalmia. Report of a joint WHO/UNICEF/USAID/Helen Keller International/IVACG meeting. Geneva: World Health Organization. 1982. Ref.: https://goo.gl/5gqir2
Indicators for assessing vitamin A deficiency and their application in monitoring and evaluation intervention programmes. Geneva: World Health Organization. 1996. Ref.: https://goo.gl/78RYoQ
Prashant Bhushan, Deepak Mishra, Singh MK, Gyan Prakash Singh. Preventions and cures for xerophthalmia; a re-visit. Int J Cur Bio Med Sci. 2012; 2: 203-204.