Custard Apple Seed Induced Bilateral Toxic Keratoconjunctivitis - A Case Report
Article Sidebar
Main Article Content
Abstract
Custard apple is a tropical fruit that is cultivated all over India. The seeds of this fruit are found to have medicinal properties as they contain active compounds such as alkaloids, cyclohexapeptides, and acetogenins. It has been used in powdered form for the treatment of scalp lice and dandruff in our part of the world as a native medicine for a long time. We report a case of bilateral severe toxic keratoconjunctivitis following accidental exposure to custard apple seed powder.
Article Details
Copyright (c) 2025 Chellakumar V.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Dastur JF. Medicinal Plants of India and Pakistan. Bombay: D.B. Taraporevala Sons; 1962. Available from: https://opac.narc.gov.np/opac_css/index.php?lvl=notice_display&id=2258
Nagaraja H, Kugar T, Shivanna Y, Agrawal A, Shetty R. Ocular toxicity by seeds of Annona squamosa (custard apple). Indian J Ophthalmol. 2016;64:611-3. Available from: https://doi.org/10.4103/0301-4738.191514
Devi Nivean P, Malarkodi S, Nishanth M, Nivean M. Custard apple seed induced keratitis: A harmful traditional practice in South India. GMS Ophthalmol Cases. 2017;7:Doc23. Available from: https://doi.org/10.3205/oc000074
Gandhi P, Radhakrishnan N, Khaitan I, Srinivasan M, Prajna VN. Toxic keratitis after application of custard apple seed for head lice infestation. Cornea. 2019;38:948-50. Available from: https://doi.org/10.1097/ico.0000000000001981
Gonde (Ballamwar) P. Custard apple seeds induced toxic keratoconjunctivitis. Glob J Cataract Surg Res Ophthalmol. 2024;3:116-8. Available from: https://gjcsro.com/custard-apple-seeds-induced-toxic-keratoconjunctivitis/
Allen PH. Poisonous and injurious plants of Panama. Am J Trop Med Hyg. 1943;23:76. Available from: https://www.cabidigitallibrary.org/doi/full/10.5555/19432901017